| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f07d2ff10aba4f23580e38140283861 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4375
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-439 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-529 |
| filingDate |
2018-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2021-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d08a5fe02d5feb8352e530fc24615219
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcfce602eff6f5f3c99f7ec8567e230e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0113cc0c5832058d95c15c1cac836fe5 |
| publicationDate |
2021-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-11198694-B2 |
| titleOfInvention |
HDAC6 inhibitors, with improved solubility and their uses |
| abstract |
The present invention relates to small molecule compounds and their use as HDAC inhibitors and their use in the treatment of various diseases, such as cancer. The present invention further relates to methods for improvement of solubility by introducing basic substituents which offer the opportunity to create pharmaceutically acceptable salts. Moreover, it comprises methods of synthesizing the compounds and methods of treatment. |
| priorityDate |
2017-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |