http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11156622-B2

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filingDate 2017-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb5f600e6395846226b733dd8b95f0f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22c87dbb899b049e83545b9fa7f5ea6d
publicationDate 2021-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-11156622-B2
titleOfInvention Molecularly-imprinted-polymer coated conductive nanoparticles for cotinine detection, and associated devices and methods
abstract A device for detecting cotinine includes (a) a film that includes a plurality of molecularly-imprinted-polymer (MIP) coated conductive nanoparticles having specific affinity for binding with cotinine, and (b) two electrodes in contact with the film for passing electrical current through the film to detect binding with cotinine as a change in electrical conductivity of the film. A MIP coated conductive nanoparticle for detecting cotinine includes (a) a conductive nanoparticle, (b) a silicon dioxide coating formed on the conductive nanoparticle and forming a first shell around the conductive nanoparticle, and (c) an MIP coating formed on the silicon dioxide coating and forming the second shell, wherein the MIP coating includes a polymer molecularly imprinted with cotinine to provide specific affinity for binding of cotinine to the MIP coated conductive nanoparticle such that the cotinine is detectable as a change in electrical conductivity of the MIP coated conductive nanoparticle.
priorityDate 2016-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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