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filingDate 2017-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59f4d62c78b960ac95c7a69ab7067ae1
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publicationDate 2021-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-11149319-B2
titleOfInvention Systems and methods for detecting cells using engineered transduction particles
abstract Accurate measurements of the presence or absence of a target cell in a sample are provided. For example, the sample can be mixed with a plurality of transduction particles capable of binding to the target cells, the transduction particles being engineered to include a nucleic acid molecule formulated to cause the target cells to produce a plurality of detectable reporter molecules once the particles bind to and deliver the nucleic acid molecules into the one or more target cells. A set of signal data points are received that are associated with a quantity of reporter molecules and the signal data points are analyzed to accurately detect target cells in the sample. Systems and methods are disclosed.
priorityDate 2016-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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