abstract |
The disclosure relates to a method for fermentation integrated with separation and purification of acetone, butanol, and ethanol (ABE) or butanol alone, comprising the following steps: 1) obtaining ABE by fermentation using an acetone-butanol-producing bacterium or obtaining butanol using a butanol-producing bacterium; 2) using a “vapor-stripping-vapor-permeation” method (briefly VSVP) for online separation and purification of ABE or purifying butanol from the fermentation broth; wherein the VSVP method comprises the following steps: introducing a gas bubble into the fermentation broth comprising active cells for fermentation to vaporize ABE or Butanol; subjecting the gas along with the vaporized ABE or Butanol to a membrane separation unit to pass through the membrane; recovering ABE or Butanol, or subjecting ABE or Butanol to a next separation device. By using the disclosed method, production, separation, and purification efficiency of ABE or butanol are improved with saved energy consumption and without increasing equipment investment. |