| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4209354dce74930bf7d6913c8065e76b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0f4ef39131394f4ff77012c1366b83ea |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D203-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-842
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-821
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2231-326
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2231-325
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2540-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-847
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-845 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-183
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-347
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-1815 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-347
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D203-24 |
| filingDate |
2020-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2021-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73507c0805ef1d9feae3ee616ad34a16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d7e3d6fee5cc4178b66d521ee56c9bc |
| publicationDate |
2021-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-11117123-B2 |
| titleOfInvention |
Compositions and methods for catalysts based on bridged chiral amidoporphyrins and their metal complexes |
| abstract |
In one aspect, the disclosure relates to a mode of asymmetric induction in radical processes based on enhanced hydrogen-bonding capability and the situation of metal centers in cavity-like chiral environments. Also disclosed is an asymmetric system for stereoselective synthesis of cyclopropane and aziridine derivatives. The disclosed Co(II)-based metalloradical system has been shown to have an unusual capability of controlling both the degree and sense of asymmetric induction in cyclopropanation and aziridination reactions in a systematic manner. The disclosed system is applicable to a broad scope of substrates having diazo or azido moieties and exhibits a remarkable profile of reactivity and selectivity, providing access to cyclopropane diastereomers and aziridine enantiomers in highly enantioenriched forms. Also disclosed are catalysts useful in the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| priorityDate |
2019-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |