| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_48df6bc4ebf937c660e36d97dec66663 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-252
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-622 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3813
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-383
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3675
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3804 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36 |
| filingDate |
2019-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2021-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f609e50937ef5d79e9ab27d344122935
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a357b7004107812094dc337000aa0584
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cda22570ec8e5435e7107af19ac44b0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ff85f0bbad61b2831042de823499aca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2cd8c59019615c27f49dd4cd2cd15ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6ccad23bf9b1ff72b9bccf1989e687d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7c406550d4c35b7ba90d77206f4880c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1af7f015f8399a965f26c87b31377d79
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c15e761f4b372c6d1fa7c36486a584a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e27bcdc1b73a99c2d9230281ec45b0aa |
| publicationDate |
2021-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-11110202-B1 |
| titleOfInvention |
Construction and application of differentially regulated tissue-engineered nerve grafts |
| abstract |
A differential tissue-engineered nerve including motor-like nerves and sensory-like nerves. The motor-like nerve and the sensory-like nerve respectively includes a motor-like nerve outer tube and a motor-like nerve fiber in the outer tube as well as a sensory-like nerve outer tube and a sensory-like nerve fiber in the outer tube. Schwann cells and/or fibroblasts derived from motor nerves and sensory nerves are respectively contained in surfaces or pores of the motor-like and sensory-like nerve outer tubes. Transsynaptic signal molecules Neuroligin-1 and Neuroligin-2 are contained in surfaces or pores of the motor-like and sensory-like nerve fibers. Neuroligin-1 is selectively used to specifically promote synaptic remodeling of motor neurons, while Neuroligin-2 is selectively used to specifically promote synaptic remodeling of sensory neurons, so that repair efficiency of motor nerve cells and sensory nerve cells is improved. |
| priorityDate |
2019-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |