Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8cf2caf35a4f97a4534d8923f7fd25a4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-382 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-96433 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
filingDate |
2017-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2021-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75ffa0520d0ab40a8c61c3dab4a20d84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0e38395cc23872f6ccbcae800fb4d16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e12dc9d52dfcdd67fa425ef134937356 |
publicationDate |
2021-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-11104703-B2 |
titleOfInvention |
Binding compound and uses thereof |
abstract |
Described are compounds for targeting proteases, e.g. serine proteases and their use in the diagnostic methods and methods for treatment of respiratory diseases such as cystic fibrosis. The compounds have the structure [H]—[B]-[A]; wherein [H] is a hydrophilic group, [B] is a subsite recognition group and [A] is a binding group; wherein A has the formula: —C(0)—CH 2 —NR 1 —COOR 2 and wherein [B] has the structure: (i) —[CO—CH 2 —NR 3 ]m-, or (ii) -[AA1-AA2]- or (iii) -(AA1-C0-CH 2 NR 3 )— or (iv) —(CO—CH 2 —NR 3 -AA1)- or (v) —(C0—CH 2 —NR 4 -AA1-AA3)-. |
priorityDate |
2016-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |