Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68c213ba9952360f439567152e047b18 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869 |
filingDate |
2018-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2021-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d1115f64bd165f48fcba8fd3b471ac2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54cf651fbf6826731f86b4a8b481e292 |
publicationDate |
2021-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-11098342-B2 |
titleOfInvention |
Time lapse sequencing: a convertible-nucleoside approach to enrichment-free analysis of RNA dynamics |
abstract |
The invention provides methods and compositions for generating mutations in new nucleic acid molecules through incorporation of a transformable nucleoside into the nucleic acid and subsequent transformation of the nucleoside through oxidative-nucleophilic-aromatic-substitution chemistry, referred to as TimeLapse chemistry. The invention further provides methods for detecting the mutations, referred to as TimeLapse-seq. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11578354-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021214768-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11174504-B2 |
priorityDate |
2017-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |