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filingDate 2018-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30187ceae46d60b7e6a18bd32a86ff74
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publicationDate 2021-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-11091791-B2
titleOfInvention Methods for hybridization based hook ligation
abstract Provided herein are compositions, methods, and kits for enriching for one or more nucleic acid sequences of interest in a sample. The methods include providing a circular ligase, one or more 5′ hook probes and/or one or more 3′ hook probes and contacting the sample comprising the nucleic acids with the circular ligase and one or more 5′ hook probes and/or one or more 3′ hook probes under conditions to allow the hook probes to selectively bind to the one or more nucleic acid sequences of interest, and under conditions to form one or more hook products, each hook product comprising the hook probes and the one or more nucleic acid sequences of interest.
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priorityDate 2017-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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