Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b79ea1c6c25451ae6f7c31cb9e750417 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4b443c70d8ccdd0e8017b5ace1ca5ff5 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6855 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2521-501 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6813 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-161 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2018-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2021-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30187ceae46d60b7e6a18bd32a86ff74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d92fec1fc683581741785959bf968cf |
publicationDate |
2021-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-11091791-B2 |
titleOfInvention |
Methods for hybridization based hook ligation |
abstract |
Provided herein are compositions, methods, and kits for enriching for one or more nucleic acid sequences of interest in a sample. The methods include providing a circular ligase, one or more 5′ hook probes and/or one or more 3′ hook probes and contacting the sample comprising the nucleic acids with the circular ligase and one or more 5′ hook probes and/or one or more 3′ hook probes under conditions to allow the hook probes to selectively bind to the one or more nucleic acid sequences of interest, and under conditions to form one or more hook products, each hook product comprising the hook probes and the one or more nucleic acid sequences of interest. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11680285-B2 |
priorityDate |
2017-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |