| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d94da17bad7b1e82edf7147e4b90731a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5398c96ec6b3c97f74f7e86bac0da421
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b2ad3543e524739b3e167d2076458755
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f278ab8fb471c7f78279bde9b4eda8a1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79877fea580c760d6284f8706f569cc2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-31 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-167
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-3276
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-26 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-167
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115 |
| filingDate |
2020-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2021-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d74e4990f80a76e63fba29df0ad7abe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d492c26d7e207e0bfcfb30d303ab4daa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_610a7fcfa774a1874bef4b04c67458b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec98c250f41a1ce3331512de7802bd63 |
| publicationDate |
2021-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-11060095-B2 |
| titleOfInvention |
Method for isolating cross-reactive aptamer and use thereof |
| abstract |
The subject invention provides a SELEX strategy for isolating cross-reactive aptamers that recognize a core structure of a small-molecule family and bind to several structurally-similar molecules in the family. The subject invention also provides methods, assays, and products for detecting small-molecule targets of the family in a sample in both clinical and field settings. Such method is based on an aptamer sensor that reports the presence of small-molecule targets via a sensitive colorimetric signal for naked-eye detection. The subject invention further provides exonuclease-based methods for generating structure-switching aptamers from fully folded aptamers and developing electrochemical aptamer-based (E-AB) sensors for rapid and sensitive detection of synthetic cathinones. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11408850-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11656235-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11579110-B2 |
| priorityDate |
2018-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |