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filingDate 2016-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4469526e828345b0be9c66d44557ac07
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publicationDate 2021-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-11028431-B2
titleOfInvention Detection of short homopolymeric repeats
abstract The present application relates to detection of changes in the number of nucleotides in short homopolymeric nucleic acid repeats, in particular in short homopolymeric microsatellites, for example for the purpose of diagnosing microsatellite instability (MSI) and/or mismatch repair (MMR-) deficiency in tumors. Accordingly, methods are provided for detecting changes in the number of nucleotides present in short homopolymeric nucleotide repeat sequences as well as kits and cartridges for automated detection of said changes.
priorityDate 2015-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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