| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2eb708c6c80673271bd975b9a0665b9 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-085 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 |
| filingDate |
2019-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2021-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a15507da36106816c1581a2b55119f52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f45afb72c69e584e0d68e6404ec0f25f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba0db800d2a000f0de3181e788176706
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e620a925ebeea82934a3cc9abd0985fd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cd27f1309d1462e20acf759495e57ca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d791739d2415afb1b870570312b2405 |
| publicationDate |
2021-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-11028425-B2 |
| titleOfInvention |
Diagnosis and monitoring of liver disease |
| abstract |
Methods and compositions for screening or diagnosis of liver disease are provided. The results may also indicate course and efficacy of treatment. The composition includes an activity sensor and a reporter releasably attached to the activity sensor. The method includes detecting the presence and/or amount of a reporter. The reporter is released from an activity sensor in the presence of diseased liver tissue but remains attached to the activity sensor in healthy tissue. The presence and/or amount of the reporter are used to characterize the liver disease. The liver disease may be nonalcoholic steatohepatitis (NASH) and results may further indicate staging of NASH. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020249229-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023076638-A3 |
| priorityDate |
2018-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |