| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c3c03868c3cbb1941929d9d8bc3f664
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_845dee65a3b9073bfd5dd429d700d189
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84f7d80cd488b854d48becf202e30738 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-515
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-66 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-66 |
| filingDate |
2018-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2021-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f848f2f07988ee30413865b4226fd7ca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d634ceaa54e0f0cac7d7dd81dc0e84e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5aa384f4ccd147d0eab4ccb10017ff6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_864583062cd888f2a10ec035a9726bf9 |
| publicationDate |
2021-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-11008293-B2 |
| titleOfInvention |
5-carboxamide-2-thiobarbituric acids and use thereof as medicaments |
| abstract |
The invention relates to a class of 5-carboxamide-2-thiobarbituric acid derivatives which inhibits human type II topoisomerase (topoII) enzyme and to use thereof as medicaments especially for blocking the proliferation of cancer cells and treating cancer. The invention also provides a method for the manufacture of the 5-carboxamide-2-thiobarbituric acid derivatives. |
| priorityDate |
2017-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |