Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc2b03342511abc88f60c63f2acd96d0 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-091 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-548 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65512 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-605 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-098 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-655 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-09 |
filingDate |
2020-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2021-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d8094a9f0f5df0cb166a308832ddb23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c00a8cda887f6f42c8a8fcd411ba3731 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_424699b56bf53e2f086b65c48b2ea5ef |
publicationDate |
2021-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10961263-B2 |
titleOfInvention |
Cell-penetrating, guanidinium-rich oligophosphotriesters for drug and probe delivery |
abstract |
Guanidinium-rich oligophosphotriesters transporter compounds and methods of making and using the same are provided. Also provided are pharmaceutical compositions that include the subject transporter compounds, where the transporter can be joined to a cargo of interest, and is formulated with a pharmaceutically acceptable excipient. Formulations may be provided in a unit dose, where the dose provides an amount of the compound effective to afford a desired therapeutic effect. Methods of using the subject transporter compounds to deliver a cargo moiety to a cell are provided, where the method can include contacting a target cell with the transporter compound. The subject methods can be performed in vitro or in vivo. |
priorityDate |
2015-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |