Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b55c349b43c3ecba4977fd52cc8f8c67 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-197 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-385 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 |
filingDate |
2019-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2021-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_693888771b93eca48282727f21ce1555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c016a99d925eff48f3a265e4d649fc81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d9c94fb0fc96f78492837b4d648d04f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ebe71dd2ec4b96087be874149a71973d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f33856fd545b808ca63a37ba29543aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4f68066c8f7e63b8176d3d9c32af4e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_814f16f5af252b2ccaef4b2f944b21bd |
publicationDate |
2021-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10952973-B2 |
titleOfInvention |
Production method of pregabalin-containing composition and pregabalin-containing composition |
abstract |
Provided are a production method of a pregabalin-containing composition, which suppresses crystallization of pregabalin, and a pregabalin-containing composition that shows suppressed crystallization of Pregabalin. The production method of the pregabalin-containing composition of the present invention contains steps of:n (1) dissolving pregabalin in an aqueous solution of an acid to prepare an aqueous solution of a salt of pregabalin; (2) mixing the aqueous solution of pregabalin salt and a hydrophilic resin to prepare a mixture thereof; and (3) concentrating the mixture; wherein the acid has an acid dissociation constant lower than that of pregabalin. |
priorityDate |
2018-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |