http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10905691-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b81c3ecc9a3bd192c754216816991d8a |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2202-24 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-0082 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L2-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L2-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate | 2019-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ceca400f9bec27249456c185b171295f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e6b1c39b78af6efeb59962d493f3bc0 |
publicationDate | 2021-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-10905691-B2 |
titleOfInvention | Use of triazolo(4,5-d)pyrimidine derivatives for prevention and treatment of bacterial infection |
abstract | A method for treatment of a bacterial infection in a host mammal in need of such treatment or a method of administering to the host mammal an effective amount of a Triazolo(4,5-d)pyrimidine of formula(I): n nwherein R 1 is C 3-5 alkyl optionally substituted by one or more halogen atoms; R 2 is a phenyl group, optionally substituted by one or more halogen atoms; R 3 and R 4 are both hydroxyl; R is XOH, wherein X is CH 2 , OCH 2 CH 2 , or a bond, and wherein when X is a bond, R is OH; or a pharmaceutical acceptable salt, provided that when X is CH 2 or a bond, R 1 is not propyl; when X is CH 2 and R 1 is CH 2 CH 2 CF 3 , butyl or pentyl, the phenyl group at R 2 must be substituted by fluorine; when X is OCH 2 CH 2 and R 1 is propyl, the phenyl group at R 2 must be substituted by fluorine. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11434241-B2 |
priorityDate | 2016-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 136.