http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10882811-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5cf9bbe3e413bdf4cafd4f536300e8ae |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-157 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-52 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-00 |
filingDate | 2017-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7043058900e6541dba1b8ec64bd0acf2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25cd57f35e8567eeec651f5c85442299 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_256cabd327f1850ccd338e9eb217c0d9 |
publicationDate | 2021-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-10882811-B2 |
titleOfInvention | Synthesis of lysine acetylsalicylate glycine particles |
abstract | The invention relates to a method for the production of acetylsalicylic acid lysinate, optionally lysine acetylsalicylate.glycine, comprising the following steps: a) providing a solution of acetylsalicylic acid in ethanol; b) providing an aqueous solution of lysine; c) combining the solutions of step a) and b) to form a mixture; d) optionally stirring the mixture; e) adding acetone to the mixture; f) incubating the mixture, to allow the formation of a acetylsalicylic acid lysinate product; g) isolating the acetylsalicylic acid lysinate product; wherein acetylsalicylic acid is used in excess compared to lysine and wherein no seed crystals are added to the mixture; and optionally the following further steps: h) providing a recrystallized glycine; wherein the glycine has been recrystallized with the following steps: h1) dissolving glycine in water; h2) adding acetone to the glycine solution; h3) stirring the mixture until a precipitate is obtained; i) combining the recrystallized glycine of step h) with the acetylsalicylic acid lysinate product of step g) to obtain lysine acetylsalicylate.glycine (LASAG) particles. |
priorityDate | 2016-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 90.