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filingDate 2017-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10815284-B2
titleOfInvention Fusion protein comprising antifreeze protein and human epidermal growth factor with increased anti-oxidant activity and skin cell proliferation effect and cosmetic composition for anti-wrinkle comprising the same as effective component
abstract A fusion protein has the amino acid sequence of SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7 or SEQ ID NO: 8. A composition having the fusion protein may improve skin wrinkle with increased anti-oxidant activity and skin cell proliferation effect. It can be advantageously used as a raw material of a functional cosmetic having an excellent skin regeneration effect like improvement of skin wrinkles and skin whitening.
priorityDate 2016-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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