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filingDate 2015-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7e361438c4a30f3246205a2adf6430e
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publicationDate 2020-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10808022-B2
titleOfInvention IL-15/IL-15Ralpha based conjugates purification method
abstract The present invention relates to a method for preparing a composition comprising monomeric conjugates from a sample, said conjugate comprising (a) a polypeptide comprising the amino acid sequence of interleukin 15 or derivatives thereof, and (b) a polypeptide comprising the amino acid sequence of the sushi domain of IL-15Rα or derivatives thereof; wherein said method comprises the use of anion-exchange chromatography followed by a hydrophobic interaction chromatography; and to a pharmaceutical composition which can be obtained by such a method.
priorityDate 2014-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID9545
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID457529135
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID449620703

Total number of triples: 303.