http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10781480-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7d39b5b2924544bd5264e177cd68f746 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-682 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2018-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f5a7ca0d9633967d172808b7af3fb98 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d7a49c514e6a2e02d4a7135f507463e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c389307f40cac499dae7c6c3f6f2b1a |
| publicationDate | 2020-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-10781480-B1 |
| titleOfInvention | Method of detecting nucleic acids with amplified signal using nanoparticles |
| abstract | A method of detecting nucleic acids with an amplified signal utilizes first and second amplification nanoparticles. The method includes hybridizing a first segment and a second segment of a target sequence with a first capture probe on capture particles and a second capture probe on first amplification nanoparticles, respectively, and forming a capture particle-target-first amplification nanoparticle complex; adding second amplification nanoparticles and hybridizing the second linker probes on second amplification nanoparticles with first linker probes on the first amplification nanoparticles in the complex, wherein a ratio of the first linker probes to the second capture probes on first amplification particles is from about 1:1 to 50:1; hybridizing reporter probes with third linker probes on the second amplification nanoparticles, wherein a ratio of the third linker probes to the second linker probes on the second amplification particles is from about 3:1 to 20:1; and detecting signals from the reporter probes. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022226251-A1 |
| priorityDate | 2017-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.