Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f4cde8ce9bc53f808c36c467c649cde5 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-02011 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-16 |
filingDate |
2018-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2020-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef22918a3371afb1fe6eccd86924db8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99edcaac1b5cbf03f61bdd4723043fb9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0097658a64865df886fe249ca42d0d04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_430990cbc36458221b85703debdb017d |
publicationDate |
2020-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10774317-B2 |
titleOfInvention |
Engineered enzyme having acetoacetyl-CoA hydrolase activity, microorganisms comprising same, and methods of using same |
abstract |
The disclosure provides engineered enzymes that are capable of mediating the conversion of acetoacetyl-CoA to acetoacetate that do not react with the same order of magnitude with acetyl-CoA as they do with acetoacetyl-CoA (e.g., the engineered enzymes have a specific acetoacetyl-CoA hydrolase activity at least 10× higher than its acetyl-CoA hydrolase activity). Additionally, the disclosure provides modified microorganisms that comprise the engineered enzymes disclosed herein and methods of using same. |
priorityDate |
2013-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |