| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_716e9a2606ffd4ba1a2a3917e4a402fd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b6c4d2f1368350d09bc34c3fdadac45 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-662
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B63-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B57-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-4009
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-405
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-40 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-662
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B63-00 |
| filingDate |
2017-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2020-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89f4a3cafcb0b6d18fc3d5ccab039d8e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce1c81469b11d38118545ab74fc9be7f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7839c818af1f29c478c413203095b8a9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b63da4fbc6da0e3e6ebce61c63bc9d55 |
| publicationDate |
2020-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-10774098-B2 |
| titleOfInvention |
Nahlsgen optical resolution method |
| abstract |
Provided is a method for separating the four optical isomers of Nahlsgen. The method according to the present invention for producing a mixture of a D-2-amino-4-[(Rp)-(3-carboxymethylphenoxy)(methoxy)phosphoryl]butanoic acid hydrate and an L-2-amino-4-[(Sp)-(3-carboxymethylphenoxy)(methoxy)phosphoryl]butanoic acid hydrate includes subjecting a mixture of the four optical isomers, represented by Formula (1′), to fractional crystallization from water or from a solvent mixture of water and a water-soluble organic solvent, to precipitate a mixture of a compound represented by Formula (1-1′-1) and a compound represented by Formula (1-4′-1), where Formulae (1′), (1-1′-1), and (1-4′-1) are expressed as follows: |
| priorityDate |
2016-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |