http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10759739-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8cfe4d98015afb6ce0269fe898d987a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-58 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| filingDate | 2016-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79e091ceface22f40c1a9fce8a9974bf |
| publicationDate | 2020-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-10759739-B2 |
| titleOfInvention | P62-ZZ small molecule modulators |
| abstract | A compound, or a pharmaceutically acceptable salt thereof, having a formula I of: n n n n n n n n n n n n wherein Ar is an arylene or heteroarylene; n n n R 1 has a structure of: n n n n n n n n n n n n n n wherein W is an alkanediyl, alkenediyl, a carbonyl, or a combination thereof; n X is —NR 5 —, wherein R 5 is H or an alkyl, or —O—; and n Y is optionally-substituted cycloalkyl, optionally-substituted cycloalkyl-substituted alkyl, optionally-substituted heterocycloalkyl, or optionally-substituted heterocycloalkyl-substituted alkyl; n n n each R 2 is the same or different and has a structure of: n n n n n n n n n n n n n n wherein Z is —NR 6 —, wherein R 6 is H or an alkyl, —O—, —S—, or —CH 2 —; n Z 1 is (—CH 2 —) m wherein m is 0 to 5, or an alkenediyl having 2 to 6 carbon atoms; n Cy is a 3-8-membered cycloalkyl, heterocycloalkyl, aryl or heteroaryl ring; and n each R 4 is the same or different and is selected from hydroxy, halogen, substituted or unsubstituted alkoxy, substituted or unsubstituted alkyl, or amino; and c is 0 to 5; and n each R 3 is the same or different and is selected from hydroxy, halogen, substituted or unsubstituted alkoxy, substituted or unsubstituted alkyl, amino, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or a nitro, n wherein a is 2 to 5, and b is 0 to 3. |
| priorityDate | 2015-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 633.