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filingDate 2017-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a6d8566f73ebd024f65928f54f7535c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b33ed110221002ef56ef0c0a7958d693
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publicationDate 2020-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10751408-B2
titleOfInvention Compositions and methods for making and using thermostable immunogenic formulations with increased compatibility of use as vaccines against one or more pathogens
abstract Embodiments of the present disclosure provide novel compositions, methods of use and methods for single composition, multi-dose, thermostable vaccine formulations. In certain embodiments, the present disclosure provides compositions and methods for dehydrating immunogenic agents in the presence of glass-forming agents, and coating the particles formed by the glass-forming agents. In other embodiments, the present disclosure provides for generating compositions for administering an immunogenic composition to a subject multiple times using a single immunogenic composition capable of time-release administration. In other embodiments, single-dose immunogenic agent-containing particles can be directed to two or more pathogens. In other embodiments, incompatible immunogenic agents against two or more different pathogens of immunogenic agent-containing particles disclosed herein can be mixed together and coated for timed-release administration to produce single-administration formulations capable of eliciting an immune response to the two or more pathogens in a subject.
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCE1WGG9
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID11292
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ05203
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8FGN5
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID186184
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID454479250
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP02879
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID165295
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID457707770
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID7427
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID457707758
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID11072
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID433322677
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ02551
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID747
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9XTQ5
http://rdf.ncbi.nlm.nih.gov/pubchem/taxonomy/TAXID48410
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID139
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9JLF7
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID452259897

Total number of triples: 318.