| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eea0de26b3bb22f02747a50127aba633 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1825
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-575 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 |
| filingDate |
2016-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2020-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b663575f321fd972c4560cc6bf10f37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b7213242eb6caf4d8d4acd7b5aeaa6e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fde849f29378ccd1c89ef17af046dee |
| publicationDate |
2020-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-10744185-B2 |
| titleOfInvention |
Methods of using variants of FGF19 polypeptides for the treatment of pruritus |
| abstract |
Provided herein are variants of fibroblast growth factor 19 (FGF19) proteins and peptide sequences (and peptidomimetics) and fusions of FGF19 and/or fibroblast growth factor 21 (FGF21) proteins and peptide sequences (and peptidomimetics), and variants of fusions of FG-F19 and/or FGF21 proteins and peptide sequences (and peptidomimetics). In some embodiments, these variants and fusions modulate bile acid homeostasis, and are useful in treatment of bile acid related and associated disorders. In some embodiments, these variants and fusions have glucose lowering activity, and are useful in treatment of hyperglycemia and other disorders. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11241481-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11103554-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11065302-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11066454-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11141460-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11370841-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11564972-B2 |
| priorityDate |
2015-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |