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filingDate 2015-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d5ac9a286838cd65bf4a53d9f444eb0
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publicationDate 2020-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10744088-B2
titleOfInvention Method for preparing ophthalmic preparation containing thymosin beta-4
abstract The present invention relates to a method for manufacturing an ophthalmic preparation comprising thymosin β4. According to the inventive method, the manufacture of an ophthalmic preparation comprising thymosin β4 is carried out in the presence of an inert gas, thus the contact of thymosin β4 with oxygen is blocked and the oxidation of thymosin β4 can be prevented and the pharmacological activity of thymosin β4 maintains for long-term period. Therefore, the ophthalmic preparation prepared by the inventive method can maintain the pharmacological activity of thymosin β4 in a stable state for a long time.
priorityDate 2015-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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