| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1271c5dc0f9289574052f5fa187c0fc7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0f060df09c5568d50105a635b687abf4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_65b1240ca9d1d061ed49c733b1dc65ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_03137a86b9a6853982367192b5037a03 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-347
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-705 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6878 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate |
2016-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2020-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b816975ad1d5a67d1cca1569dc7cb0b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_474ad1c6e2fa05b1a3effa70e88a2633
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bbf61a23addcabfb616eb6496b77f8b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31ac929dbb3e4223d81b85b46c885a2c |
| publicationDate |
2020-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-10739356-B2 |
| titleOfInvention |
Prognosis and monitoring of membranous nephropathy based on the analysis of PLA2R1 epitope profile and spreading |
| abstract |
Disclosed is a method for assessing the prognosis of idiopathic membranous nephropathy in a body fluid sample from a human subject, based on profiling PLA2R1 epitopes recognized by autoantibodies in the sample. The method further relates to analysis of PLA2R1 epitope spreading amongst three PLA2R1 domains (Cys R, CTLD1 and CTLD7) that are recognized by anti-PLA2R1 autoantibodies, two of which (CTLD1 and CTLD7) are more closely associated with active idiopathic membranous nephropathy and likely linked by a mechanism of epitope spreading. |
| priorityDate |
2015-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |