http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10730881-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate | 2019-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de6be8cc84d79459d55ea96bb08b929e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bff5def3bdd3543b33ae974810aae831 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_209259f9f93ce12923b6dae8f91c4a70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38ac7eae8de7a28ad13b5fbdb95db25c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83413618aa6a15ca8b99b862f10a8ecf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_589e637640a348954dfd7929f1080661 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fec48dbe44a05f0f0c3b39b8934bdb03 |
| publicationDate | 2020-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-10730881-B2 |
| titleOfInvention | Fused pyrimidine derivatives |
| abstract | The present invention relates to a compound of formula I n nwhereinn R 1 is phenyl, lower alkyl, C 3-6 -cycloalkyl, —CH 2 —C 3-6 -cycloalkyl or bridged C 4-6 -cycloalkyl, substituted by one, two or three halogen atoms, or by lower alkyl or lower alkyl substituted by halogen; R 2 is a five or six membered heteroaryl group, selected from nn n n n n n n n n n n n wherein n R 6 is hydrogen, lower alkyl, halogen or lower alkoxy; and n R 7 is hydrogen, lower alkoxy or halogen; n n n R 3 is lower alkyl or lower alkyl substituted by hydroxy: n R 4 is hydrogen or lower alkyl; n R 5 is hydrogen or lower alkyl; n n is 1 or 2; n -( ) n - is —CH 2 — or —CH 2 CH 2 — for n being 1 or 2;n nor to a pharmaceutically active acid addition salt thereof, to a racemic mixture or to its corresponding enantiomer and/or optical isomer and/or stereoisomer thereofn n n n The compounds may be used for the treatment of Alzheimer's disease, cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica or Down syndrome. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10875854-B2 |
| priorityDate | 2016-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 746.