http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10716836-B2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2519a8a24265d332d553ed57391f8a49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_26b1584f27f58599de7d99065046a3d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d1bf3e008c4ff31c5f042f50649af41b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a029a044829964683b18eccf3a85d0d5 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-515 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0008 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783 |
filingDate | 2008-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4be2c2278d454892f2ea5a1d93fdfe55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2878e6d127ee91a4a6b3063ba0a0613 |
publicationDate | 2020-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-10716836-B2 |
titleOfInvention | Methods for treating autoimmune disease by inducing autoantigen-specific regulatory CD4+ T cells |
abstract | Described herein are methods and compositions for the treatment and monitoring the progress of autoimmune diseases. In some embodiments, the methods include the stimulation of regulatory T cells specific to autoantigens associated with the autoimmune disease. A specific embodiment relates to diabetes mellitus, and the prevention or delay of loss of residual β-cell mass, providing a longer remission period and delaying the onset of diabetes related, progressive, complications through immunotherapeutic induction of regulatory T cells specific for human insulin B chain. In addition, the methods described herein can be used to predict whether a subject, e.g., a subject with ongoing anti-insulin autoimmunity, will progress to T1DM, and to evaluate a subject's response to a therapeutic intervention. |
priorityDate | 2006-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1177.