http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10696709-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4c0cf6d13d2539db84c38b6e28882c0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-207 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-207 |
| filingDate | 2017-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9ac1372694e8213d03ec720bd0be7a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b5290eaaa4e6e31da82717d8e7ffe18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18cb77870224b233999411a6e87e3f56 |
| publicationDate | 2020-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-10696709-B2 |
| titleOfInvention | Phosphotriazole MRNA 5′-end cap analogs, composition comprising the same, RNA molecule incorporating the same, uses thereof and method of synthesizing RNA molecule, protein or peptide |
| abstract | The object of the invention is a compound of formula (I), or a stereoisomer or salt thereof, wherein R 1 and R 2 are selected from the group consisting of N, N+—CH 3 , N + —C 2 H 5 , N + —C 3 H 8 , N + —C 4 H 5 , N + —CH 2 C 6 H 5 wherein at least one of R 1 , R 2 is not N. n and m are independently chosen from the group consisting of 0, 1 and 2; X is selected from the group consisting of O, NH, S, CH 2 k is 1 or 2 Y is either void or selected from the group of —CH 2 —, —CH 2 CH 2 —, —CH 2 O—, —CH 2 S—, —CH 2 NH—, —CH 2 CH 2 O—, —CH 2 CH 2 NH—, —CH 2 CH 2 S— R 3 , R 4 , R 5 , R 6 are selected from the group consisting of H, OH, OCH 3 , or OCH 2 CH 3 ; wherein R 3 and R 4 may be the same or different; R 5 and R 6 may be the same or different; if either of R 3 , R 4 is different than OH than R 5 and R 6 are both OH; if either of R 5 , R 6 is different than OH than R 3 and R 4 are both OH. The object of the invention is also a composition comprising the compound of the invention, an RNA molecule incorporating the same, uses thereof and a method of synthesizing, in vitro or in vivo, the RNA molecule, as well as a method of synthesizing a protein or peptide in vitro, or in vivo or in cultured cells, said method comprising translating the RNA molecule. |
| priorityDate | 2016-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 342.