Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2caaba601fd6460c7b37706d920d42e2 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-09 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 |
filingDate |
2016-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2020-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a445acc0459ca0bbf1a078a028ad83e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2cf910199a79c1f1295fee1e3ac399d9 |
publicationDate |
2020-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10695398-B2 |
titleOfInvention |
Method of treating prostate cancer with GnRH antagonist |
abstract |
The invention provides methods and dosing regimens for safely and effectively treating androgen-dependent prostate cancer with a gonadotrophin releasing hormone (GnRH) antagonist without causing a testosterone spike and/or other side effect of GnRH agonist therapy such as a urinary tract infection, or an arthralgia-related or cardiovascular side effect. The present disclosure also provides for methods for treating prostate cancer in a patient with a history of at least one cardiovascular event, wherein administration of degarelix to the subject decreases the likelihood of developing or experiencing an additional cardiovascular event compared to treatment with a gonadotrophin releasing hormone (GnRH) agonist. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE49353-E http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11766468-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11491149-B2 |
priorityDate |
2008-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |