Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_51f8c4298ee7818439743df297034684 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-12 |
filingDate |
2017-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2020-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab1ce1252d0324b9bdc30176eef646f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e0023f206a5a1ff8a5565c12f000e99 |
publicationDate |
2020-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10662152-B2 |
titleOfInvention |
Crystalline pharmaceutical co-crystals of glycopyrronium bromide with lactose |
abstract |
The present invention provides co-crystals of glycopyrronium bromide with lactose. The glycopyrronium bromide and lactose in the novel co-crystals are present in a stoichiometric ratio of from about 1:2 to 2:1. These are characterized by XRD and DSC. Processes for preparing the novel co-crystals are also provided. The co-crystals are also disclosed for use as a medicament, in particular, for treatment of respiratory complaints, such as chronic pulmonary obstructive disease (COPD), bronchitis and asthma. Pharmaceutical compositions comprising the co-crystals as active ingredient are also presented. |
priorityDate |
2016-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |