http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10626080-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c8955ecf9b783d3b8ad169586b2ea1fd |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-08 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-608 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C405-0041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-608 |
| filingDate | 2017-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_618502fdd9cddd8fce2d5e889f98a7db http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1528d677185b8e4596af2b2b45666a67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83fb77b6daba6824daa084341887fb0b |
| publicationDate | 2020-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-10626080-B2 |
| titleOfInvention | Process for the preparation of bimatoprost |
| abstract | It is provided a process for the preparation of bimatoprost, which comprises: a) reacting a compound of formula (III) with ethylamine in the presence of a suitable solvent; and b) deprotecting compound obtained in step a) to obtain bimatoprost, wherein R 1 is selected from (C 1 -C 16 )alkyl, (C 1 C 16 )haloalkyl, (C 2 -C 16 )alkenyl, (C 2 -C 16 )haloalkenyl, (C 1 -C 16 )alkoxy(C 1 -C 16 )alkyl, aryl, (C 1 -C 16 )alkylaryl, allyl, —(CH 2 —CH 2 —O) n —CH 3 wherein n=1, 2, 3 or 4, and —CH(O—CH 2 —CH 2 ) 2 ; R 2 is selected from H, (C 1 -C 16 )alkyl, (C 1 -C 16 )haloalkyl, (C 2 -C 16 )alkenyl, (C 2 -C 16 )haloalkenyl, (C 1 -C 16 )alkoxy(CrC 16 )alkyl, aryl, (C 1 -C 16 )alkylaryl, allyl; or, alternatively, R 1 and R 2 taken together are selected from —CH 2 —CH 2 —CH 2 —, —CH 2 —CH 2 —, —O—CH 2 —CH 2 —, and —O—CH═CH—. There are also provided intermediates useful in such preparation process. |
| priorityDate | 2016-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 210.