http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10619189-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1543b2b19ec0e331a0dcd89888cbef5f |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2527-125 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6844 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2527-125 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6844 |
filingDate | 2016-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_322158cbbcd6e075f0f7d419931e47bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4e70819b492432babd81d606e6cd60a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af476cc74cdda8561b2b52b997142c3f |
publicationDate | 2020-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-10619189-B2 |
titleOfInvention | Composition for reducing inhibition of nucleic acid amplification |
abstract | A composition for reducing the inhibitory effects of contaminants on nucleic acid amplification is provided. The composition includes a plurality of zirconium oxide particles, a non-ionic surfactant, and an organic iron-chelating reagent. The organic iron-chelating reagent has a first affinity constant greater than or equal to 104.2 with respect to ferric iron and a second affinity constant less than 103.8 with respect to magnesium, wherein the first affinity constant and the second affinity constant are determined in deionized water at pH 8.45 and 20° C. Optionally, the composition includes polyvinylpyrrolidone. Optionally, the composition comprises water. The composition has a pH of about 8.45 to 8.85. Methods of using the composition to prepare a sample for nucleic acid amplification are also provided. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023031691-A1 |
priorityDate | 2015-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 384.