Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8cfe4d98015afb6ce0269fe898d987a |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2016-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2020-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fb042e1e9eaa25e2780a8adf876beb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9a0cbfbc060167b8908670fd1adc0dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c801eb57be490a5c032c40012a83ebf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdde77b01166353a074cbb53118bb52f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b98790eaa086740212ed444c83bf543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6124ebe0aa8d6b185f9d3ead9bec3219 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc69a3b9d134ff460f014ef93995e46f |
publicationDate |
2020-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10618914-B2 |
titleOfInvention |
6-aryl-7-substituted-3-(1H-pyrazol-5-yl)-7H-[1,2,4]triazolo[3,4-B][1,3,4]thiadiazines as inhibitors of the STAT3 pathway with anti-proliferative activity |
abstract |
Compounds that selectivity inhibit the STAT3 pathway and not the STAT1 pathway and exhibit anti-proliferative activity are disclosed. Also disclosed are methods of treatment of cancers that are characterized by overexpression of STAT3, which are safer that other therapies. |
priorityDate |
2015-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |