http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10617650-B2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5089 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
filingDate | 2016-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adf978d5dc6bd3b9383ba05ebfc09342 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd7f001d40383af7a0549c8d87bb0d82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d030d92f6570a1a3c9ca6d05ae247cde http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e8a3680c451406fa7616614014cc72e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ef0ae1a60dc65536099aefa7edd72f8 |
publicationDate | 2020-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-10617650-B2 |
titleOfInvention | Process for preparing formulations for gastrointestinal-targeted therapies |
abstract | The present invention provides a process for preparing enterically-coated lyospheres comprising a therapeutic agent comprising: a.) providing lyospheres comprising the therapeutic agent; b.) coating said lyospheres with an enteric polymer coating composition; and c.) isolating said enterically-coated lyospheres. In other embodiments, the invention provides dosage forms comprising a lyosphere comprising an effective amount of a therapeutic agent and an enteric polymer coating. In some embodiments, the therapeutic agent in the process or dosage form is a polypeptide, a protein, a peptide, a lipopeptide, a glycoprotein, a fusion protein, a protein conjugate, a cytokine, an enzyme, an antibody, an oligonucleotide, a vaccine vector, small molecule, a live virus, an inactivated virus, a virus-like particle, a viral protein subunit, an adjuvant, microbiome, a prebiotic, a probiotic, or an ectobiotic. In some embodiments of the present invention, after oral administration the dosage forms containing the enterically-coated lyospheres provide a method of delivering a therapeutic agent to the ileum, ileo-caecal junction, colon or a combination thereof in a subject. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11672761-B2 |
priorityDate | 2015-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 345.