| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac316c4307d2a84add2bae0328f607bd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bf4713e1115d298fe25a10684c5d0fa6 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15043 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 |
| filingDate |
2017-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2020-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00e66076d1df8ecf237846b323de12c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e16a73efcb26c77195901609dd557124
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55095109f2279170c8ca8471785796a2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55330555dd13c6769072f1b8e129f3cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22730df6194044593f0d8dfb8e2e1101 |
| publicationDate |
2020-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-10590434-B2 |
| titleOfInvention |
Highly inducible dual-promoter lentiviral TET-ON system |
| abstract |
The invention relates to expression systems useful for regulated expression of a gene of interest based on the constitutive expression of the original TetR repressor and the expression of the polynucleotide driven by a constitutive promoter operably linked to an operator sequence for a tetracycline operator sequence. The system can be provided as two different polynucleotides or as an all-in-one vector. The invention also relates to vectors, host cells and viral particles according to the invention as well as to the uses thereof for in vitro and in vivo production of products of interest or for therapy. |
| priorityDate |
2011-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |