| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_797d329258dc5e7944651a166d610a71 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C319-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C319-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-58 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-59 |
| filingDate |
2018-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2020-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_deb737a962ae1271aaa0d1674b3490f5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11212cdccad26f2411a25c5439b7163e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a773d3ae88d234dd71744be827f340c5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65f6f38fa67bdb1bbd6d39e805906698
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab81da86be7fa6f2707490d5ccffa094 |
| publicationDate |
2020-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-10590073-B2 |
| titleOfInvention |
Method for preparation of N-acetyl cysteine amide and derivatives thereof |
| abstract |
The present invention includes methods for making and isolating N-acetylcysteine amide, intermediates and derivatives thereof comprising: contacting cystine with an alcohol and a chlorinating reagent to form an organic solution containing L-cystine dimethylester dihydrochloride; combining dried or undried L-cystine dimethylester dihydrochloride with a triethylamine, an acetic anhydride, and an acetonitrile to form a di-N-acetylcystine dimethylester; mixing dried di-N-acetylcystine dimethylester with ammonium hydroxide to form a di-N-acetylcystine amide; and separating dried di-N-acetylcystine dimethylester into N-acetylcysteine amide with dithiothreitol, triethylamine and an alcohol. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11548851-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11091433-B2 |
| priorityDate |
2017-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |