| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_299e61160b333bde03bc2fd31dcf5752 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5161 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 |
| filingDate |
2016-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2020-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba62bdab3e06520b1bb0390cf0b2a50e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_547497a10a40c2339a2a442f8ee2bb32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_324de7efc9b1b9fcaa06755bd233e243
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b289c3c0b360a7a14766f00d90f2e08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c64ed851bfa8e1caee467b74fa006fe4 |
| publicationDate |
2020-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-10583142-B2 |
| titleOfInvention |
Pulse dosing regimen and methods of treatment |
| abstract |
A novel dosing regimen for erlotinib or a pharmaceutically acceptable salt thereof is described herein. The dosing regimen demonstrates impressive control of central nervous system disease, which is better than that reported with standard dose erlotinib. The use of the novel dosing regimen for treating patients in need thereof, including for controlling formation of metastatic brain, leptomeninges, or CNS lesions in a patient with non-small cell lung cancer (NSCLC) that harbors epidermal growth factor receptor (EGFR) mutation with or without pre-existing brain metastases, is also described herein. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022133725-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11253520-B2 |
| priorityDate |
2016-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |