Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e96496a9949403e2af2ca913e65bfec |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-85 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6901 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
filingDate |
2014-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2020-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c24f8e03659f1c9ff3b9824a8f92939c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f249bf7b944cf1788c16ffb1ce93c10c |
publicationDate |
2020-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10538570-B2 |
titleOfInvention |
Targeted and modular exosome loading system |
abstract |
Disclosed are exosomes that include a packaging protein and a cargo RNA in which the packaging protein binds specifically to the cargo RNA. The packaging protein is a fusion protein that includes an RNA-binding domain and an exosome-targeting domain. The cargo RNA includes an RNA-motif that the RNA-binding domain of the fusion protein binds specifically such that the cargo RNA is packaged in the lumen of the exosomes. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020317746-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11236143-B2 |
priorityDate |
2013-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |