| abstract |
Embodiments provide, among things, compounds of the formula I: n nwherein Het, Y, R x , Z, X, R 1 -R 3 , R 6 , and R 7 are defined herein; and methods for using such compounds to reduce pain (e.g., neuronal pain), treat a mammal's addiction to nicotine or anti-pain drugs, and increase a mammal's sensitivity to drugs that bind MOR or NMDAR. |