http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10512639-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ceb3b5e59a6335b315a8d20d5231b3aa |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-502 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
filingDate | 2019-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f0b6b5bc614e89c18a4f699a4a9fdf6 |
publicationDate | 2019-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-10512639-B1 |
titleOfInvention | Therapeutic agents for treating diseases associated with chronic inflammation and screening method |
abstract | A method for treating autoimmune diseases or a disease associated with chronic inflammation can include administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising an Arid5a inhibitor and a pharmaceutically acceptable carrier. The Arid5a inhibitor can have the formula n nor a pharmaceutically acceptable salt thereof. The disease associate with chronic inflammation can be multiple sclerosis. A screening method can include identifying candidate Arid5a inhibitors through in silico predicted binding to Arid5a target domains and confirming Arid5a inhibition through in vitro binding assays. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11654138-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10709696-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021186944-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022003439-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020222101-A1 |
priorityDate | 2019-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 262.