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grantDate 2019-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2019-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10501410-B2
titleOfInvention Pocess for the preparation of high purity prostaglandins
abstract The subject of the invention is a process for the preparation of high purity prostaglandin acid of the general formula II wherein the bonds marked with dotted lines represent single or double bonds wherein the double bonds may be cis- or trans oriented, Y represents O or CH 2 , and R 3 stands for a phenyl group which is optionally substituted with CF 3 , wherein the crude prostaglandin acid of the general formula II is purified by normal phase silicagel chromatography.
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