Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_caacf483b6be9ae2d2677103a70559db |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-74 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C49-83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-76 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-76 |
filingDate |
2017-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2019-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9b49e63148f485b3e8fc44a7ed5e2e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f48dc65f6654a169ac2b2f32c5a3b2e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_628d71763c27316964317048b3f8ac9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e070153f1993a07fe9d8e9b513fccf62 |
publicationDate |
2019-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10494383-B2 |
titleOfInvention |
Method for preparing difluoroallylboronate and application thereof |
abstract |
The present invention relates to a method for preparing difluoroallylboronate and application thereof, and it belongs to a field of compound preparation. A method for preparing difluoroallyl borate ester is using a compound of the formula II and bis (pinacolato) diboron as raw materials in a solvent and in the presence of an iron catalyst and a base according to the following reaction formula, to obtain a compound of the formula I, n nThe method of the present invention directly use an inexpensive, commercially available metal iron salt as a catalyst to provide a convenient, low-cost method for preparing difluoroallyl borate ester, and provide a new and effective approach for the synthesis of γ-aminobutyric acid receptor agonist (III). |
priorityDate |
2016-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |