Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_faf522b8b83eded745c73018576219ba |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-0689 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00662 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00734 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00331 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0819 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00317 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-0046 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502769 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-5085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48721 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-487 |
filingDate |
2014-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2019-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87611151d6c43f9582dce44d70557373 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_890430c1b153d2e9c42783b17a4c7e59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cabed606c34685ac28b8f62f5e33e24d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f33eba10c2d5f5492430a07e148a61e8 |
publicationDate |
2019-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10471429-B2 |
titleOfInvention |
High-density microchamber array and manufacturing method thereof |
abstract |
A material film is formed as a thin film having a thickness of 1 μm on a surface of a glass substrate. A plurality of micro-chambers having a diameter of 5 μm are formed in the material film to be arrayed at a high density. The respective chambers filled with an aqueous test solution have openings that are liquid-sealed by a lipid bilayer membrane to provide a high-density micro-chamber array. Significant downsizing of the micro-chambers enhances a change in concentration by a reaction of one biomolecule in the chamber and thereby increases the detection sensitivity. In the configuration that a large number of micro-chambers are formed at a high density, even in the case of an extremely slow reaction of the biomolecule, the reaction proceeds in any of the chambers. This configuration accordingly enables the reaction of the biomolecule to be detected with high sensitivity. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11041198-B2 |
priorityDate |
2013-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |