| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ab5a7b5f39157c7a9ce35b4db7b84162 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0215 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-02 |
| filingDate |
2016-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2019-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a8ebce56c324100cf38ea40392c045b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f6bde125facebc0da2c2664b6096729
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6edc0d3ccf8f981aa2083520ecd81f7b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e30bf7dbf4b62a7be52f2b6c7de66ae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b6abc5ae79d6ada806240fd06d8140c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93b0da6fadebfd9a2e9699b423e5e2bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00dd73a1f1c6ee27e39f55a2621289c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_405db36fe5faaefc7188d0775f050036 |
| publicationDate |
2019-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-10442835-B2 |
| titleOfInvention |
Water-soluble rapamycin derivatives |
| abstract |
The present invention relates to technical fields of organic chemistry and pharmaceutical chemistry, specifically to water-soluble rapamycin derivatives modified with glutathione. More specifically, the present invention discloses a compound of formula I and the preparation method thereof, wherein R 1 and R 2 are as defined in the description. The compound of formula I can be used in inducing immunosuppression and in the treatment of diseases such as transplant rejection and solid tumor, etc. |
| priorityDate |
2016-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |