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filingDate 2017-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2019-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10434171-B2
titleOfInvention Microfluidized Mycobacterium avium fragments as an adjuvant and carrier for mucosal vaccine delivery
abstract A vaccine adjuvant and immunogenic composition may be described herein. The vaccine adjuvant may comprise cell wall fragments of the genus Mycobacterium, and more particularly, of M. avium. The immunogenic composition may include the vaccine adjuvant conjugated to an antigen. For example, cell wall fragments of M. avium (herein also referred to as MAF) may be conjugated to an antigen targeting Gonadotropin releasing hormone (GnRH). The MAF-antigen conjugate may be delivered for the purposes of treatment through one of several methods, including intramuscular injection, naso-pharyngeal, or oral.
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