Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_15d42f684941d5b0617ca7764ebdff07 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2001-4083 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14151 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10351 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N15-042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-4077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-405 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-40 |
filingDate |
2016-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2019-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69aea732fb8217c13e2e348c40630706 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6eaa02dabef395d93d407153cc01b346 |
publicationDate |
2019-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10429288-B2 |
titleOfInvention |
Analytical ultracentrifugation for characterization of recombinant viral particles |
abstract |
Provided herein are methods to characterize preparations of recombinant viral particles using analytical ultracentrifugation. Recombinant viral particles include recombinant adeno-associated viral particles, recombinant adenoviral particles, recombinant lentiviral particles and recombinant herpes simplex virus particles. Variant species of recombinant viral particles including empty capsids and recombinant viral particles with variant genomes (e.g., truncated genomes, aggregates, recombinants) can be identified and quantitated. The methods can be used to characterize preparations of recombinant viral particles regardless of the sequence of the recombinant viral genome or the serotype of the recombinant viral capsid. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022099547-A1 |
priorityDate |
2015-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |