http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10428149-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ee1f2823cfb50f8cebb69de7f074d4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c70cc66c25854f28ea8816284cd8f9e |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-626 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-91 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2863 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 |
| filingDate | 2016-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36b22af1c7187a3894851ce07e6eda81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_921da1a94d00a0cb1b9e207c914c33b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be24fbc45802b8c6fe3348815ff9c7d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cc595fe3b09d2e64ba277a82d8025c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75039da1c15c46f84332027e5b0ce1de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_360bb3641955f643929c5a4ce6b0fe41 |
| publicationDate | 2019-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-10428149-B2 |
| titleOfInvention | Single-chain tumor necrosis factor (TNF) ligand family molecules, fusion proteins and derivatives thereof |
| abstract | The present invention relates to a polypeptide comprising a component A with at least three tumor necrosis factor (TNF) homology domains of TNF-ligand family members (THD) in which C-terminal and N-terminal reference points are defined by consensus sequences and which are connected through short stretches of additional C-terminal and/or N-terminal amino acids of the THD or variants thereof, and a component B comprising a dimerization domain. Further, the present invention relates to a polypeptide comprising at least three THDs in which C-terminal and N-terminal reference points are defined by consensus sequences and which are connected through short stretches of additional C-terminal and/or N-terminal amino acids of the THD or variants thereof. Further, the invention relates to a nucleic acid comprising said polypeptides, a vector comprising said nucleic acid and a pharmaceutical composition comprising said polypeptides, or said nucleic acids or said vector. Further, the present invention relates to said polypeptides, said nucleic acid or said vector for the use as a medicament or for the use in the diagnosis, prophylaxis or treatment of hyperproliferative disorders and inflammatory disorders. |
| priorityDate | 2015-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 102.