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filingDate 2013-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e761365a7c0a0db3f9baee5978085e3
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publicationDate 2019-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10420801-B2
titleOfInvention Isolation and use of human lymphoid organ-derived suppressive stromal cells
abstract A method for suppressing an immune response is provided. The method involves administration of isolated lymphoid tissue-derived suppressive stromal cells (LSSC) to a subject in need of such treatment in an amount effective to suppress the immune response in the subject. The invention also involves a method to isolate LSSC by digesting lymphoid tissue fragments using a combination of an enzyme mix and agitation and then collecting the LSSC. Pharmaceutical preparations comprising LSSC are also provided.
priorityDate 2012-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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